Benefits
- High purity ventricular phenotype
- Strong functional resemblance to human heart ventricular cardiomyocytes
- Reliable responses in electrophysiology, safety, and pharmacology assays
Product Specifications
|
Feature |
Detail |
|---|---|
|
Identity Markers |
≥ 85% cardiac Troponin T (cTnT+) by flow cytometry at Day 3; expression of ventricular marker MLC2v; sarcomeric markers (e.g. TNNT2), downregulation of progenitor/undifferentiated iPSC genes. |
|
Quantities |
≥ 1 × 10⁶ and ≥ 4 × 10⁶ viable cells |
|
Quality Control |
Cell count, viability, identity (FACS), functionality (e.g. Voltage Sensitive Dyes/Calcium Sensitive Probe: response to isoproterenol, dofetilide, nifedipine), mycoplasma testing |
|
Format |
Cryopreserved |
|
Donor & Reprogramming |
Specified donor (female/male; healthy/diseased as applicable); Sendai Virus reprogramming |
|
Shipping / Storage |
Dry shipper at -180°C to -135°C; store in vapor phase of liquid nitrogen |
|
Supplied with |
Cardiomyocyte culture medium; user-guide/instructions for thawing / seeding / maintenance / maturation |
Figure 1. Electrophysiological validation. Greenstone Biosciences ventricular cardiomyocytes baseline action potentials and response to hERG Channel blockade ( red symbols, 30nM, E4031).
Technical Data
- Clear structural sarcomere alignment, α-actinin / myosin heavy chain staining
- Action-potential recordings show fast upstroke, distinct plateau phase typical of human ventricular myocytes
- Ventricular CM APD>>Atrial CM APD
- Response to adrenergic stimulation (e.g. isoproterenol) as well as to ion channel blockers (e.g. L-type Ca²⁺ channel blockers, hERG blockers, Na channel blockers)
Explore Ventricular Cardiomyocytes
Discover our high-purity, iPSC-derived ventricular cardiomyocytes designed for cardiac safety, electrophysiology, and drug discovery research. Check out the product details to see how these cells can accelerate your studies.