Epithelial Cells

  • Epithelial Cells

Human iPSC-derived Intestinal Epithelial Cells

These organoids mimic the structure and cellular diversity of human intestinal epithelium.IPSC-derived intestinal products show a crypt-like structure, which is the common feature of intestinal epithelium. They contain enterocytes, goblet cells, Paneth cells, and enteroendocrine cells. They are valuable tools for studying gut barrier function, host-microbiome interactions, screening drugs, assessing pharmacokinetic profiles of potential medications, and testing the toxicology of possible interventions.

Benefits

  • Physiological 3D intestinal architecture
  • Contains absorptive and secretory cells
  • Suitable New Approach Method (NAM) for gut disease modeling
  • Develops a high-throughput platform for drug screening and assessing the toxicology of potential drugs.

Product Specifications

Feature

Detail

Identity Markers

Sucrase isomaltase (enterocytes), (MUC2 (goblet cells), LGR5 (stem cells), Lyz (Paneth cells)

Quantities

≥ 500 organoids/ crypt like structures per vial

Quality Control

Markers characterization , mycoplasma testing

Format

Cryopreserved

Donor & Reprogramming

Healthy/ diseased  donor-derived iPSCs; Sendai virus reprogramming

Supplied with

Handling guide and instructions for differentiation and culture