
Human iPSC-derived Fibroblasts
Widely used to study ECM remodeling, fibrosis, cell signaling, and wound repair. These fibroblasts show robust secretion of matrix proteins and support for co-culture and 3D tissue systems.
Benefits
- High expression of fibroblast markers (e.g. Vimentin, FSP1, DDR2, PDGFR-α)
- Strong ECM production, contractility in gel contraction assays
- Compatible with co-cultures, organoids, 3D matrices
Product Specifications

Figure 3. Representative immunofluorescence images showing stage-specific cells express pluripotency genes (iPSC; NANOG and SSEA4), pass through epicardial cell lineage (EPC; ZO1 and WT1) and cardiac fibroblast (CF) genes (GATA4 and DDR2) during the differentiation process. DAPI=nucleus stain. Scale bars, 100µm. From Zhang et al, Methods Mol Biol. 2022;2454:109–115. doi: 10.1007/7651_2020_300
- Identity via marker panels; QC includes viability, mycoplasma, functional assays (e.g. ECM deposition)
- Supplied cryopreserved; sizes scaled to research or higher throughput needs
- Proper donor background info available
Explore Fibroblasts
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