Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target
This study was published in the Journal Cell on Oct 12, 2024, co-authored by several Greenstone Biosciences employees in collaboration […]
Publications
Tackling the challenges of new approach methods for predicting drug effects from model systems
Excited to share our latest commentary in Nature Reviews Drug Discovery! We delve into the challenges and advancements in using
Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction
Tu C, Caudal A, Liu Y, Gorgodze N, Zhang H, Lam CK, Dai Y, Zhang A, Wnorowski A, Wu MA,
Studying Long QT Syndrome Caused by NAA10 Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells.
Belbachir N, Wu Y, Shen M, Zhang SL, Zhang JZ, Liu C, Knollmann BC, Lyon GJ, Ma N, Wu JC.
Statins improve endothelial function via suppression of epigenetic-driven EndMT.
Liu C, Shen M, Tan WLW, Chen IY, Liu Y, Yu X, Yang H, Zhang A, Liu Y, Zhao MT,
FDA Modernization Act 2.0 Paves the Way to Computational Biology and Clinical Trials in a Dish
Syed Mukhtar Ahmed , PhD; Rabindra V. Shivnaraine , PhD; Joseph C. Wu , MD, PhD For nearly a century,
Researchers solve mystery of how statins improve blood vessel health
Nina Bai Statins designed to lower cholesterol have long been noted to work in mysterious ways to improve other aspects
Leveraging Physiology and Artificial Intelligence to Deliver Advancements in Healthcare
Angela Zhang, Zhenquin Wu, Eric Wu, Matthew Wu, Michael P. Snyder, James Zou, and Joseph C. Wu Greenstone Biosciences co-founded Joseph C.
Current and future perspectives of single-cell multi-omics technologies in cardiovascular research
Wilson Lek Wen Tan, Wei Qiang Seow, Angela Zhang, Siyeon Rhee, Wing H. Wong, William J. Greenleaf & Joseph C.
Shifting machine learning for healthcare from development to deployment and from models to data
Angela Zhang, Lei Xing, James Zou, Joseph C. Wu In the past decade, the application of machine learning (ML) to
Marijuana linked to heart disease; supplement may mitigate risk, study reports
Krista Conger Marijuana use and heart-attack risk were correlated in a large human study, Stanford scientists and their collaborators found.
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation
Tu C, Caudal A, Liu Y, Gorgodze N, Zhang H, Lam CK, Dai Y, Zhang A, Wnorowski A, Wu MA,
Induced pluripotent stem cell technology: a decade of progress.
Yanhong Shi, Haruhisa Inoue, Joseph C Wu, Shinya Yamanaka Since the advent of induced pluripotent stem cell (iPSC) technology a